Research areas

Our research interests lie at the interface of immune-oncology, nucleic acid theranostics, immunotherapy, and functional biomaterials. My current focus is to develop therapeutics and vaccines for combination cancer immunotherapy, infectious disease prevention, and drug abuse treatment. Current primary research directions are listed below.

• mRNA vaccines for cancer immunotherapy and infectious disease prophylaxis.

• Novel nucleic acid immunotherapeutics for cancer immunotherapy (immunomodulatory DNA/RNA, mRNA, gene-editing gRNA, siRNA, aptamer)

• ADAR-targeted nucleic acid theranostics and immunomodulators

• Drug and vaccine delivery

• Biomaterials: Nanovaccine/Nanomedicine, polymer microneedle patches, hydrogel