Publications

Publications 

(>100 peer-reviewed journal articles) (*, #: equal contribution) 

Citation > 10,000; H-index > 60 (Google Scholar)

Full publication list: Pubmed 

2019-present

Manuscripts in preparation

Zhou S, Liu X, Zhu G. RNA therapeutics and vaccines: from biology to engineering (review)

Alshehry Y, Liu X, Mao H-Q, Zhu G. Lipid nanocarriers for mRNA immunotherapeutic and vaccines (invited review)

Manuscripts under review

101. Zhang Y, Liu X, Zhang B, Zhou S, Shen T, Mei L, Chen L, Wang XY, Tyc K, Liu J, Zhu G, etc. Small circular mRNA vaccines for tumor immunotherapy (in revision, Nature Biomedical Engineering)

Published manuscripts

100. Zhou S, Cheng F, Zhang Y, Su T, Zhu G. cGAS-STING immunomodulation based on oligonucleotides and biomaterials. Accounts of Chemical Research. (In press)

99. Zhou S, Su T, Cheng F, Cole J, Liu X, Zhang B, Alam S, Liu J, Zhu G. Engineering cGAS-agonistic oligonucleotides as therapeutics and vaccine adjuvants for cancer immunotherapy. (in revision, Molecular Therapy - Nucleic Acids) See preprint in bioRxiv, 2023 (https://doi.org/10.1101/2023.07.13.548237)

98. Cheng F, Su T, Zhou S, Liu X, Yang S, Lin S, Guo W, Zhu G. Single-dose injectable nanovaccine-in-hydrogel for robust immunotherapy of large tumors with abscopal effect. Science Advances.2023, 9(28):eade6257

97. Cheng F, Su T, Liu Y, Qi J, Guo W, Zhu G. Targeting lymph nodes for systemic immunosuppression using cell-free-DNA-scavenging and cGAS-inhibiting nanomedicine-in-hydrogel for rheumatoid arthritis immunotherapy. Advanced Science. 2023, e2302575

96. Su T, Cheng F, Bos P, Valerie K, Zhu G, et al. Lymph node-targeting albumin-binding DNA scaffold for the codelivery of adjuvant and neoantigens in combination tumor immunotherapy. Theranostics. 2023, 13 (13), 4304

95. Dain L, Zhu G. Nucleic acid immunotherapeutics and vaccines: a promising approach to glioblastoma multiforme treatment. International Journal of Pharmaceutics. 2023. 638:122924

94. Su T, Liu X, Lin S, Cheng F, Zhu G. Ionizable polymeric nanocarriers for the codelivery of bi-adjuvant and neoantigens in combination tumor immunotherapy. Bioactive Materials. 2023. 26:169-180

93. Tan X, Zhao Z, Wang R, Zhu G. Molecular and Nanoscale Engineering of Nucleic Acid Theranostics and Vaccines. Frontiers in Bioengineering and Biotechnology. 2023. 10:1126876 (Editorial)

92. Chen J, Li R, Knapp S, Zhu G, Whitener RL, Leiter EH, Mathews CE. Intergenomic and epistatic interactions control free radical mediated pancreatic β-cell damage. Frontiers in Genetics. 2022. 13:994501

91. Liu X, Zhang Y, Zhou S, Dain L, Mei L, Zhu G. Circular RNA: an emerging frontier in RNA therapeutic targets, RNA therapeutics, and mRNA vaccines. Journal of Controlled Release 2022 348, 84-94

90.   Su T, Lin S#, Zhu G#, et al. pH-responsive multifunctional polymer nanovaccines of STING agonist and neoantigen for cancer immunotherapy. Advanced Science 2022 9 (23), 2201895

89. Tang W#, Zhu G#. Pulmonary delivery of mucosal nanovaccines. Nanoscale. 2022 14 (2), 263-276

88.     Shen T, Zhang Y, Mei L, Zhang X#, Zhu G#. Circular DNA for theranostic applications. Theranostics. 2022 12 (1), 35

87.    Su T, Liu X, Zhou S, Ahmed NT, and Zhu G#. STING activation and STING nanovaccines for cancer immunotherapy. (Book Chapter. Editors: Drs. Mansoor M. Amiji, Lara Milane) 2022 353-373

86.     Su T, Cheng F, Pu Y, Cao J, Lin S#, Zhu G#, He B. Polymeric micelles amplify tumor oxidative stresses through combining PDT and glutathione depletion for synergistic cancer chemotherapy. Chemical Engineering Journal. 2021, 411: 128561.

85.     Hu L, Chen W, Zhou S, and Zhu G#. ExoHCR: a sensitive assay to profile PD-L1 level on tumor exosomes for immunotherapeutic prognosis. Biophysics Report. 2020, 6:290–298

84.     Zhang Y, Shen T, Zhou S, Wang W, Lin S#, Zhu G#. pH-responsive STING-activating nanovaccines for cancer immunotherapy. Advanced Therapeutics. 2020 https://doi.org/10.1002/adtp.202000083

83. T Shen, Y Zhang, S Zhou, S Lin, X Zhang, G Zhu. Nucleic acid immunotherapeutics for cancer . ACS Applied Bio Materials.  2020  https://doi.org/10.1021/acsabm.0c00101​

82. Zhou S, Chen W, Cole J (undergraduate researcher), Zhu G. Delivery of nucleic acid therapeutics for cancer immunotherapy. Medicine in Drug Discovery. 2020. https://doi.org/10.1016/j.medidd.2020.100023​

81. Ni Q, Zhang F, Wang Z, Niu G, Lu G, Su T, Zhu G#, Zhang L#, Chen X#. A bi-adjuvant nanovaccine that potentiates immunogenicity of neoantigen for combination immunotherapy of colorectal cancer.. Science Advances. 2020 Mar 18;6(12):eaaw6071. doi: 10.1126/sciadv.aaw6071. eCollection 2020 Mar. PMID: 32206706​

80. Su T, Zhang Y, Valerie K, Wang XY, Lin S, Zhu G. STING activation for cancer immunotherapy. Theranostics. 2019 Oct 15;9(25):7759-7771. ​

79. Zhang Y, Lin S#, Wang XY,  Zhu G#. Nanovaccines for cancer immunotherapy. WIREs Nanomedicine & Nanobiotechnology. 2019 Jun 6:e1559. doi: 10.1002/wnan.1559. ​

78. Lin LS, Wang JF, Song J, Liu Y, Zhu G, Dai Y, Shen Z, Tian R, Song J, Wang Z, Tang W, Yu G, Zhou Z, Yang Z, Huang T, Niu G, Yang HH, Chen ZY, Chen X. Cooperation of endogenous and exogenous reactive oxygen species induced by zinc peroxide nanoparticles to enhance oxidative stress-based cancer therapy. Theranostics. 2019 Sep 23;9(24):7200-7209.​

77. Liu Y, Gong CS, Dai Y, Yang Z, Yu G, Liu Y, Zhang M, Lin L, Tang W, Zhou Z, Zhu G, Chen J, Jacobson O, Kiesewetter DO, Wang Z, Chen X. In situ polymerization on nanoscale metal-organic frameworks for enhanced physiological stability and stimulus-responsive intracellular drug delivery. Biomaterials. 2019. doi: 10.1016/j.biomaterials.2019.119365​

76. Tian R, Zhu S, Zeng Q, Lang L, Ma Y, Kiesewetter D, Liu Y, Fu X, Lau J, Zhu G, Jacobson O, Wang Z, Dai Y, Yu G, Brooks B, Liu G, Niu G, Chen X. An albumin sandwich enhances in vivo circulation and stability of metabolically labile peptides. Bioconjugate Chemistry. 2019 May 13. doi: 10.1021/acs.bioconjchem.9b00258. [Epub ahead of print]

​75. Shan L, Gao G, Wang W, Tang W, Wang Z, Yang Z, Fan W, Zhu G, Zhai K, Jacobson O, Dai Y, Chen X. Self-assembled green tea polyphenol-based coordination nanomaterials to improve chemotherapy efficacy by inhibition of carbonyl reductase 1. Biomaterials. 2019 Jul;210:62-69. doi: 10.1016/j.biomaterials.2019.04.032. Epub 2019 May 1.​

74. Yang W, Zhu G, Wang S, Yu G, Yang Z, Lin L, Zhou Z, Liu Y, Dai Y, Zhang F, Shen Z, Liu Y, He Z, Lau J, Niu G, Kiesewetter DO, Hu S, Chen X. In Situ Dendritic Cell Vaccine for Effective Cancer Immunotherapy. ACS Nano. 2019 Mar 26;13(3):3083-3094. doi: 10.1021/acsnano.8b08346. Epub 2019 Mar 7.

​73. He Z, Dai Y, Li X, Guo D, Liu Y, Huang X, Jiang J, Wang S, Zhu G, Zhang F, Lin L, Zhu JJ#, Yu G#, Chen X#. Hybrid Nanomedicine Fabricated from Photosensitizer-Terminated Metal-Organic Framework Nanoparticles for Photodynamic Therapy and Hypoxia-Activated Cascade Chemotherapy. Small. Jan. 2019, doi: 10.1002/smll.201804131. [Epub ahead of print]

​72. Cheng S, Jacobson O, Zhu G#, Chen Z, Liang SH, Tian R, Yang Z, Niu G#, Zhu X#, Chen X #. PET imaging of EGFR expression using an 18F-labeled RNA aptamer. European Journal of Nuclear Medicine and Molecular Imaging. 2019, 46(4): 948-956.

Before 2019

​71. Ni Q, Pham N, Meng W, Zhu G#, Chen X#. Advances in the immunotherapy of type I diabetes. Advanced Drug Delivery Review. 2018, doi: 10.1016/j.addr.2018.12.003. [Epub ahead of print]

​70. Shen Z, Liu T, Li Y, Lau J, Yang Z, Fan W, Zhou Z, Shi C, Ke C, Bregadze VI, Mandal SK, Liu Y#, Li Z, Xue T, Zhu G, Munasinghe J, Niu G, Wu A#, Chen X#. Fenton-reaction-accelerable magnetic nanoparticles for ferroptosis therapy of orthotopic brain tumors. ACS Nano. 2018, 12(11):11355-11365.

​69. Zhu G, Chen X. Aptamer-based targeted therapy. Advanced Drug Delivery Review. 2018, 134:65-78.

​68. Ni Q*, Zhang F*, Zhang Y*, Zhu G#, Wang Z, Teng Z, Wang C, Yung BC, Niu G, Lu G, Zhang L#, Chen X#. In Situ shRNA Synthesis on DNA-Polylactide Nanoparticles to Treat Multidrug Resistant Breast Cancer. Advanced Materials. 2018, 30(10), doi: 10.1002/adma.201705737. (Inside Cover Paper)

​67. Zhang F*, Ni Q*, Jacobson O, Cheng S, Liao A, Wang Z, He Z, Yu G, Song J, Ma Y, Niu G, Zhang L#, Zhu G#, Chen X #. Polymeric nanoparticles with a glutathione-sensitive heterodimeric multifunctional prodrug for in vivo drug monitoring and synergistic cancer therapy. Angewandte Chemie  International Edition. 2018, 57(24):7066-70.

​66. Dai Y, Yang Z, Cheng S, Wang Z#, Zhang R, Zhu G, Wang Z, Yung BC, Tian R, Jacobson O, Xu C, Ni Q, Song J, Sun X, Niu G, Chen X#. Toxic reactive oxygen species enhanced synergistic combination therapy by self-assembled metal-phenolic network nanoparticles. Advanced Materials. 2018 30(8), doi: 10.1002/adma.201704877.

​65. Tian R, Jacobson O#, Niu G, Kiesewetter D, Zhu G, Ma Y, Wang Z, Liu G, Chen X#. Evans blue attachment enhances somatostatin receptor subtype-2 imaging and radiotherapy. Theranostics. 2018 8(3):735-45.

​64. Shan L, Zhuo X, Wang W, Zhu G, Gao G, Gu Y#, Chen X#. A paclitaxel prodrug with bifunctional folate and albumin binding moieties for both passive and active targeted cancer therapy. Theranostics. 2018, 8(7):2018-30

​63. Wu W, Zhang T#, Han D, Fan H, Zhu G, Ding X, Wu C, You M, Qiu L, Li J, Zhang L, Lian X, Hu R, Mu Y, Zhou J, Tan W#. Aligner-mediated cleavage of nucleic acids and its application to isothermal exponential amplification. Chemical Science. 2018, 9(11):3050-55.

​62. Zhu G, Lynn GM, Jacobson O, Chen K, Liu Y, Zhang H, Ma Y, Zhang F, Tian R, Ni Q, Cheng S, Wang Z, Lu N, Yung BC, Wang Z, Lang L, Fu X, Jin A, Weiss ID, Vishwasrao H, Niu G, Shroff H, Klinman DM, Seder RA, Chen X. Albumin/vaccine nanocomplexes that assemble in vivo for combination cancer immunotherapy. Nature Communications. 2017, 8(1):1954.

​61. Zhu G, Mei L, Vishwasrao HD, Jacobson O, Liu Y, Yung BC, Fu X, Jin A, Niu G, Wang Q, Zhang F#, Shroff H, Chen X#. Intertwining DNA-RNA nanocapsules loaded with tumor neoantigens as synergistic nanovaccines for personalized cancer immunotherapy. Nature Communications 2017, 1482. DOI:10.1038/s41467-017-01386-7.

​60. Zhang F, Zhu G#, Jacobson O, Liu Y, Chen K, Yu G, Ni Q, Fan J, Yang Z, Xu F, Fu X, Wang Z, Ma Y, Niu G, Zhao X, X Chen#. Transformative nanomedicine of an amphiphilic camptothecin prodrug for long circulation and high tumor uptake in cancer therapy. ACS Nano. 2017, 11(9):8838-48.​

59. Zhu G, Zhang F, Ni Q, Niu G, Chen X. Efficient nanovaccine delivery in cancer immunotherapy. ACS Nano. 2017, 11(3):2387-92 (Perspective)

​58. Zhu G, Zhang H, Jacobson O, Wang Z, Chen H, Niu G, Chen X. Combinatory screening of DNA aptamers for molecular imaging of HER2 in cancer. Bioconjugate Chemistry. 2017, 28(4):1068-75.

​57. Chen H, Zhang W, Zhu G, Xie J#, Chen X#. Rethinking cancer nanotheranostics. Nature Reviews Materials 2017, 2, 17024.

​56. Zhang F, Khan S, Li R, Smolen JA, Zhang S, Zhu G, Su L, Jahnke AA, Elsabahy M, Chen X, Wooley KL. Design and development of multifunctional polyphosphoester-based nanoparticles for ultrahigh paclitaxel dual loading. Nanoscale. 2017 9(41):15773-7.

​55. Liu Y, Wang Z, Liu Y, Zhu G, Jacobson O, Fu X, Bai R, Lin X, Lu N, Yang X, Fan W, Yu G, Zhang F, Kalish H, Niu G, Nie Z#, Chen X#. Suppressing nanoparticle-mononuclear phagocyte system interactions of two-dimensional gold nanorings for improved tumor accumulation and photothermal ablation of tumors. ACS Nano. 2017, 11(10):10539-48

​54. Yang X, Wang Z, Zhang F, Zhu G, Song J, Teng GJ#, Niu G#, Chen X#. Mapping sentinel lymph node metastasis by dual-probe optical imaging. Theranostics. 2017, 7 (1):153-63.

​53. Kim YH, Min KH, Wang Z, Kim J, Jacobson O, Huang P, Zhu G, Liu Y, Yung B, Niu G#, Chen X#. Development of sialic acid-coated nanoparticles for targeting cancer and efficient evasion of the immune system. Theranostics. 2017, 7(4):962-73

​52. Cheng S, Lang L, Wang Z, Jacobson O, Yung B, Zhu G, Gu D, Ma Y, Zhu X#, Niu G#, Chen X#. Positron emission tomography imaging of prostate cancer with Ga-68-labeled gastrin-releasing peptide receptor agonist BBN7–14 and antagonist RM26. Bioconjugate Chemistry. 2017, 29(2):410-9.

​51. Song J*, Wu B*, Zhou Z, Zhu G, Liu Y, Yang Z, Lin L, Yu G, Zhang F, Zhang G, Duan H#, Stucky GD#, Chen X#. Double-layered plasmonic-magnetic vesicles by self-assembly of janus amphiphilic gold-iron(II,III) oxide nanoparticles. Angewandte Chemie International Edition. 2017, 56(28):8110-4.

​50. Shen Z, Chen T, Ma X, Ren W, Zhou Z, Zhu G, Zhang A, Liu Y, Song J#, Li Z, Ruan H, Fan W, Lin L, Munasinghe J, Chen X#, Wu A#. Multifunctional theranostic nanoparticles based on exceedingly small magnetic iron oxide nanoparticles for T1-weighted magnetic resonance imaging and chemotherapy. ACS Nano. 2017, 11(11):10992-1004.

​49. Mei L, Teng Z, Zhu G, Liu Y, Zhang F, Zhang J, Li Y, Guan Y, Luo Y, Chen X#, Wang Q#. Silver nanocluster-embedded zein films as antimicrobial coating materials for food packaging. ACS Applied Materials Interfaces. 2017, 9(40):35297-304.

​48. Zhu G, Liu Y, Yang X, Kim YH, Zhang H, Jia R, Liao HS, Jin A, Lin J, Aronova M, Leapman R, Nie Z, Niu G, Chen X. DNA-inorganic hybrid nanovaccine for cancer immunotherapy. Nanoscale. 2016, 8(12):6684-92.

​47. Zhang L*, Zhu G*, Mei L, Wu C, Qiu L, Cui C, Liu Y, Teng IT, Tan W. Self-assembled DNA immunonanoflowers as multivalent CpG nanoagents. ACS Applied Materials Interfaces. 2015, 7(43):24069-74.

​46. Zhu G, Niu G, Chen X. Aptamer-drug conjugates. Bioconjugate Chemistry. 2015, 26(11):2186-97.

​45. Zhu G, Cansiz S, You M, Qiu L, Han D, Zhang L, Mei L, Fu T, Chen Z#, Tan W#. Nuclease-resistant synthetic drug-DNA adducts: programmable drug-DNA conjugation for targeted anticancer drug delivery. NPG Asia Materials. 2015, 7, e169.

​44. Mei L*, Zhu G*, Qiu L, Wu C, Chen H, Liang H, Cansiz S, Lv Y, Zhang X#, Tan W#. Self-assembled multifunctional DNA nanoflowers for the circumvention of multidrug resistance in targeted anticancer drug delivery. Nano Research. 2015, 8(11):3447-60.

​43. Trinh TL*, Zhu G*, Xiao X, Puszyk W, Sefah K, Wu Q, Tan W#, Liu C#. A synthetic aptamer-drug adduct for targeted liver cancer therapy. Plos One. 2015, 10(11):e0136673.

​42. Jacobson O*, Weiss ID*, Wang L, Wang Z, Yang X, Dewhurst A, Ma Y, Zhu G, Niu G, Kiesewetter DO, Vasdev N, Liang SH#, Chen X#. 18F-labeled single-stranded DNA aptamer for PET imaging of protein tyrosine kinase-7 expression. Journal Nuclear Medicine. 2015, 56(11):1780-5.

​41. Zhang L*, Yang Z*, Sefah K, Bradley KM, Hoshika S, Kim MJ, Kim HJ, Zhu G, Jiménez E, Cansiz S, Teng IT, Champanhac C, McLendon C, Liu C, Zhang W, Gerloff DL, Huang Z#, Tan W#, Benner SA#. Evolution of functional six-nucleotide DNA. Journal of the American Chemical Society. 2015, 137(21):6734-7.

​40. Hu R, Liu T, Zhang XB, Yang Y, Chen T, Wu C, Liu Y, Zhu G, Huan S#, Fu T, Tan W#. DLISA: A DNAzyme-based ELISA for protein enzyme-free immunoassay of multiple analytes. Analytical Chemistry. 2015, 87(15):7746-53.

​39. Lv Y, Hu R, Zhu G, Zhang X#, Mei L, Liu Q, Qiu L, Wu C, Tan W#. Preparation and biomedical applications of programmable and multifunctional DNA nanoflowers. Nature Protocol. 2015, 10(10):1508-24.

​38. You M, Zhu G, Chen T, Donovan MJ, Tan W. Programmable and multiparameter DNA-based logic platform for cancer recognition and targeted therapy. Journal of the American Chemical Society. 2015, 137(2):667-74.

​37. Li J, Wu S, Wu C, Qiu L, Zhu G, Cui C, Liu Y, Hou W, Wang Y, Zhang L, Teng IT, Yang HH#, Tan W#. Versatile surface engineering of porous nanomaterials for in vivo tumor targeting and therapy. Nanoscale. 2015, 8(16):8600-6.

​36. Zhou C, Chen T, Wu C, Zhu G, Qiu L, Cui C, Hou W, Tan W. Aptamer CaCO3 nanostructures: a facile, pH-responsive, specific platform for targeted anticancer theranostics. Chemistry - an Asian Journal. 2015, 10(1):166-71.

​35. Qiu L, Chen T, Öçsoy I, Yasun E, Wu C, Zhu G, You M, Han D, Jiang J, Yu R, Tan W. A cell-targeted, size-photocontrollable, nuclear-uptake nanodrug delivery system for drug-resistant cancer therapy. Nano Letters. 2015, 15(1):457-63.

​34. He Q, Kiesewetter DO, Qu Y, Fu X, Fan J, Huang P, Liu Y, Zhu G, Liu Y, Qian Z#, Chen X#. NIR-responsive on-demand release of CO from metal carbonyl-caged graphene oxide nanomedicine. Advanced Materials. 2015, 27(42):6741–6.

​33. Song E#, Han W, Li C, Cheng D, Li L, Liu L, Zhu G, Song Y, Tan W#. Hyaluronic acid-decorated graphene oxide nanohybrids as nanocarriers for targeted and pH-responsive anticancer drug delivery. ACS Applied Materials Interfaces. 2014, 6(15):11882-90.

​32. Huang F, You M, Chen T, Zhu G, Liang H#, Tan W#. Self-assembled hybrid nanoparticles for targeted co-delivery of two drugs into cancer cells. Chemical Communications. 2014, 50(23):3103-5.

​31. Li C, Chen T, Ocsoy I, Zhu G, Yasun E, You M, Wu C, Zheng J, Song E, Huang CZ#, Tan W#. Gold-coated Fe3O4 nanoroses with five unique functions for cancer cell targeting, imaging, and therapy. Advanced Functional Materials. 2014, 24(12):1772-80.

​30. Wang R, Zhu G, Mei L, Xie Y, Ma H, Ye M, Qing FL, Tan W. Automated modular synthesis of aptamer-drug conjugates for targeted drug delivery. Journal of the American Chemical Society. 2014, 136(7):2731-4.

​29. Sefah K*, Yang Z*, Bradley KM, Hoshika S, Jiménez E, Zhang L, Zhu G, Shanker S, Yu F, Turek D, Tan W#, Benner SA#. In vitro selection with artificial expanded genetic information systems. Proceedings of the National Academy of Sciences of the United States of America. 2014, 111(4):1449-54.

​28. Hu R, Zhang X, Zhao Z, Zhu G, Chen T, Fu T, Tan W. DNA nanoflowers for multiplexed cellular imaging and traceable targeted drug delivery. Angewandte Chemie - International Edition. 2014, 53(23):5821-6.

​27. Qiu L, Zhang T, Jiang J, Wu C, Zhu G, You M, Chen X, Zhang L, Cui C, Yu R, Tan W. Cell membrane-anchored biosensors for real-time monitoring of the cellular microenvironment. Journal of the American Chemical Society. 2014, 136(38):13090-3.

​26. Liu Y*, Chen T*, Wu C, Qiu L, Hu R, Li J, Cansiz S, Zhang L, Cui C, Zhu G, You M, Zhang T, Tan W. Facile surface functionalization of hydrophobic magnetic nanoparticles. Journal of the American Chemical Society. 2014, 136(36):12552-5.

​25. Meng HM, Zhang X#, Lv Y, Zhao Z, Wang NN, Fu T, Fan H, Liang H, Qiu L, Zhu G, Tan W#. DNA dendrimer: an efficient nanocarrier of functional nucleic acids for intracellular molecular sensing. ACS Nano. 2014, 8(6):6171-81.

​24. Zhu G, Zheng J, Song E, Donovan M, Zhang K, Liu C, Tan W. Self-assembled, aptamer-tethered DNA nanotrains for targeted transport of molecular drugs in cancer theranostics. Proceedings of the National Academy of Sciences of the United States of America. 2013, 110(20):7998-8003. (Highlighted by NCI Alliance for Nanotechnology in Cancer, Nanomedicine, Nano today, University of Florida, Gainesville Sun, etc.)

​23. Zhu G*, Hu* R, Zhao Z, Chen Z, Zhang X, Tan W. Noncanonical self-assembly of multifunctional DNA nanoflowers for biomedical applications. Journal of the American Chemical Society. 2013, 135(44):16438-45. (Highlighted by Nature’s Science-Business Exchange (SciBX), etc.)

​22. Zhu G, Zhang S, Song E, Zheng J, Hu R, Fang X, Tan W. Building fluorescent DNA nanodevices on target living cell surfaces. Angewandte Chemie - International Edition. 2013, 52(21):5490-6. (Frontispiece cover paper)

​21. Wang J, You M, Zhu G, Shukoor MI, Chen Z, Zhao Z, Altman MB, Yuan Q, Zhu Z, Chen Y, Huang CZ#, Tan W#. Photosensitizer-gold nanorod composite for targeted multimodal therapy. Small 2013, 9(21):3678-84.

​20. Wu C*, Han D*, Chen T, Peng L, Zhu G, You M, Qiu L, Sefah K, Zhang X, Tan W. Building a multifunctional aptamer-based DNA nanoassembly for targeted cancer therapy. Journal of the American Chemical Society. 2013, 135(49):18644-50

​19. Zheng J, Zhu G, Li Y, Li C, You M, Chen T, Song E, Yang R#, Tan W#. A spherical nucleic acid platform based on self-assembled DNA biopolymer for high-performance cancer therapy. ACS Nano. 2013, 7(8):6545-54.

​18. Han D, Zhu G, Wu C, Zhu Z, Chen T, Zhang X, Tan W. Engineering a cell-surface aptamer circuit for targeted and amplified photodynamic cancer therapy. ACS Nano. 2013, 7(3):2312-19.

​17. Qiu L, Wu C, You M, Han D, Chen T, Zhu G, Jiang J, Yu R, Tan W. A targeted, self-delivered, and photocontrolled molecular beacon for mRNA detection in living cells. Journal of the American Chemical Society. 2013, 135(35):12952-5.

​16. Wu C*, Chen T*, Han D, You M, Peng L, Cansiz S, Zhu G, Li C, Xiong X, Jimenez E, Yang CJ, Tan W. Engineering of switchable aptamer micelle flares for molecular imaging in living cells. ACS Nano. 2013, 7(7):5724-31.

​15. Ocsoy I, Gulbakan B, Chen T, Zhu G, Chen Z, Sari MM, Peng L, Xiong X, Fang X, Tan W. DNA-guided metal-nanoparticle formation on graphene oxide surface. Advanced Materials. 2013, 25(16):2319-25.

​14. Xiong X, Wu C, Zhou C, Zhu G, Chen Z, Tan W. Responsive DNA-based hydrogels and their applications. Macromolar Rapid Communications. 2013, 34(16):1271-83.

​13. Zhu G, Ye M#, Donovan MJ, Song E, Zhao Z, Tan W#. Nucleic acid aptamers: an emerging frontier in cancer therapy. Chemical Communications. 2012, 48(85):10472-80.

​12. Zhu G, Meng L, Ye M, Yang L, Sefah K, O'Donoghue MB, Chen Y, Xiong X, Huang J, Song E, Tan W. Self-assembled aptamer-based drug carriers for bispecific cytotoxicity to cancer cells. Chemistry - an Asian Journal. 2012, 7(7):1630-36.

​11. Tan X, Chen W, Lu S, Zhu Z, Chen T, Zhu G, You M, Tan W. Molecular beacon aptamers for direct and universal quantitation of recombinant proteins from cell lysates. Analytical Chemistry. 2012, 84(19):8272-6.

​10. Tan X, Chen T, Xiong X, Mao Y, Zhu G, Yasun E, Li M, Zhu Z, Tan W. Semiquantification of ATP in live cells using nonspecific desorption of DNA from graphene oxide as the internal reference. Analytical Chemistry. 2012, 84(20):8622-7.

​9. Han D*, Zhu Z*, Wu C, Peng L, Zhou L, Gulbakan B, Zhu G, Williams KR, Tan W. A logical molecular circuit for programmable and autonomous regulation of protein activity using DNA aptamer-protein interactions. Journal of the American Chemical Society. 2012, 134(51):20797-804.

​8. Zhang K*, Sefah K*, Tang L, Zhao Z, Zhu G, Ye M, Sun W#, Goodison S, Tan W#. A novel aptamer developed for breast cancer cell internalization. ChemMedChem. 2012, 7(1):79-84.

​7. Jiao A, Zheng J, Hu Y, Zhu G, Li J#, Li H#, Yang R#, Tan W. Hybridization-triggered isothermal signal amplification coupled with MutS for label-free and sensitive fluorescent assay of SNPs. Chemical Communications. 2012, 48(45):5659-61.

​6. Wang J, Zhu G, You M, Song E, Shukoor MI, Zhang K, Altman MB, Chen Y, Zhu Z, Huang CZ#, Tan W#. Assembly of aptamer switch probes and photosensitizer on gold nanorods for targeted photothermal and photodynamic cancer therapy. ACS Nano. 2012, 6(6):5070-7.

​5. Kang H, Trondoli AC, Zhu G, Chen Y, Chang YJ, Liu H, Huang YF#, Zhang X#, Tan W#. Near-infrared light-responsive core-shell anogels for targeted drug delivery. ACS Nano. 2011, 5(6):5094-9.

​4. Yang L, Meng L, Zhang X#, Chen Y, Zhu G, Liu H, Xiong X, Sefah K, Tan W#. Engineering polymeric aptamers for selective cytotoxicity. Journal of the American Chemical Society. 2011, 133(34):13380-6.

​3. Huang J, Chen Y, Yang L, Zhu Z, Zhu G, Yang X, Wang K#, Tan W#. Amplified detection of cocaine based on strand-displacement polymerization and fluorescence resonance energy transfer. Biosensor Bioelectronics. 2011, 28(1):450-3.

​2. Meng L, Sefah K, O'Donoghue MB, Zhu G, Shangguan D, Noorali A, Chen Y, Zhou L, Tan W. Silencing of PTK7 in colon cancer cells: caspase-10-dependent apoptosis via mitochondrial pathway. Plos One. 2010, 5(11):e14018.

​1. Huang J, Zhu Z, Bamrungsap S, Zhu G, You M, He X, Wang K#, Tan W#. Competition-mediated pyrene-switching aptasensor: probing lysozyme in human serum with a monomer-excimer fluorescence switch. Analytical Chemistry. 2010, 82(24):10158-63

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Book chapters and general science articles

​2. Zhu G, Qiu L, Meng H, Mei L, Tan W. Aptamers-guided DNA nanomedicine for cancer theranostics. Aptamers Selected by Cell-SELEX for Theranostics (Editor: Dr. Weihong Tan) 2015, 111-37.

​1. Zhu G, Mei L, Tan W. Nanomedicine. The Scientist 2014, 28(8):28-33